Trending News
19 February, 2025
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New York
A decade ago, researchers introduced a new model for studying Alzheimer’s disease. Known as ‘Alzheimer’s in a dish,’ the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the human brain over 10 to 13 years in just six weeks. But does the model truly produce the same changes that take place in patients? In a new study, researchers created an algorithm to assess, in an unbiased manner, how well models of Alzheimer’s disease mimic the function and gene expression patterns seen in patients’ brains. Their results identify crucial shared pathways, confirming that the Alzheimer’s in a dish model can be used to assess new drugs accurately and rapidly as well as point the way to drug discovery.
A new study identifies research strategies for tying brain function and structure to behavior and health.
Chronic diseases such as diabetes are on the rise and are costly and challenging to treat. Scientists have discovered a common denominator driving these diverse diseases, which may prove to be a promising therapeutic target: proteolethargy, or reduced protein mobility, in the presence of oxidative stress.
New research, based on data from more than 28,000 caregivers in three countries, shows that the longer individuals spend caring for loved ones, the more their well-being suffers, regardless of the caregiving context. These findings underscore the need for policy discussions to alleviate the burden of informal care.
Researchers have used a new gold-based drug to slow tumor growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to a new study.
Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular ‘bridge’ complex demonstrate a new level of detail in the understanding of early neural development — which is fundamental for the further understanding of neurodevelopmental syndromes.
A decade ago, researchers introduced a new model for studying Alzheimer’s disease. Known as ‘Alzheimer’s in a dish,’ the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the human brain over 10 to 13 years in just six weeks. But does the model truly produce the same changes that take place in patients? In a new study, researchers created an algorithm to assess, in an unbiased manner, how well models of Alzheimer’s disease mimic the function and gene expression patterns seen in patients’ brains. Their results identify crucial shared pathways, confirming that the Alzheimer’s in a dish model can be used to assess new drugs accurately and rapidly as well as point the way to drug discovery.
A new study identifies research strategies for tying brain function and structure to behavior and health.